Involvement of Renal Dopaminergic System in Experimental Neurogenic Arterial Hypertension
نویسندگان
چکیده
منابع مشابه
The electrolytes of arterial wall in experimental renal hypertension.
In nits with renal hypertension, smooth muscle cells in the wall of the aorta appear to have more water, sodium, potassium, magnesium and phosphorus per unit of cell solids than similar cells in normotensive rats. When the blood pressure of a few hypertensive rats dropped to normal as a result of a low sodium diet, the potassium and phosphorus in the arterial cells also appeared to deci'ease to...
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We developed a new model to examine the role of arterial baroreceptors in the long-term control of mean arterial pressure (MAP) in dogs. Baroreceptors in the aortic arch and one carotid sinus were denervated, and catheters were implanted in the descending aorta and common carotid arteries. MAP and carotid sinus pressure (CSP) averaged 104 +/- 2 and 102 +/- 2 mmHg (means +/- 1 SE), respectively,...
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Pulmonary arterial hypertension (PAH) is a chronic pulmonary vascular disease characterized by increased pulmonary vascular resistance (PVR) leading to right ventricular (RV) failure. Autonomic nervous system involvement in the pathogenesis of PAH has been demonstrated several years ago, however the extent of this involvement is not fully understood. PAH is associated with increased sympathetic...
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Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport, vascular smooth muscle contractility and production of reactive oxygen species and by interacting with the renin-angiotensin and sympathetic nervous systems. Dopamine receptors are classified into D(1)-like (D(1) and D(5)) and D(2)-like (D(2), D(3) and D(4)) subtypes based on their st...
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• It has been well established that there is a resetting of baroceptor nerve activity in chronic experimental renal hypertension.' This, together with the fact that pithing of the brain and spinal cord lowers the blood pressure of hypertensive animals to the same low values that are found in normal animals after pithing, and that it is possible to lower the blood pressure of rats with chronic h...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 1995
ISSN: 0916-9636,1348-4214
DOI: 10.1291/hypres.18.supplementi_s187